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Personalized approaches are critical, as host genetics, diet, and baseline microbiota composition significantly influence outcomes (203, 204)

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Jian Z, Li K, Liu L, Zhang Y, Zhou Z, Li C, et al
Moreover, AML with mutations in IDH or FLT3 alters redox metabolism, potentially shifting dependence toward ferroptosis-resistant pathways [38, 169]

Yet, established clinical markers for AA remain elusive, emphasizing the need for further research in diagnostic and therapeutic modalities

Expression of MAO-B is upregulated in reactive astrocytes in the substantia nigra, leading to excessive GABA production and oxidative stress