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Studies on spearmint extract demonstrated that it improved PCOS symptoms and ovarian histology against estradiol and letrozole induced PCOS disease models (139)

Rosa, et al

Psychiatry 172 , 570578 (2015)

2 Oral spironolactone has been associated with diuretic effects, irregular menstruation, and breast tenderness

None of the toxicities were grade IV, and there were no indications of sufficient seriousness to limit further clinical development

Regulated deficit irrigation: an effective way to solve the shortage of agricultural water for horticulture
