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154 Researchers have proposed engineering bacteria to deliver therapeutic molecules or perform diagnostic functions in the gut by leveraging synthetic biology techniques

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Additionally, dimerization can stabilize proteins, helping them maintain their functional conformation and resist denaturation under physiological conditions as well as regulate intracellular signaling molecules 9,10

Eli Lilly has indicated an NDA filing in Q4 2026 at the earliest, which realistically puts an FDA decision in 2027 or later

Cheng Y, Dai X, Yang T, Zhang N, Liu Z, Jiang Y