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These changes include loss of neurons in response to a high-fat diet, with NOS neurons being particularly affected, as well as changes to receptor sensitivity (e.g., enhanced nicotinic responsivity in mice fed a high-fat diet) and other functional alterations to ENS signaling (625629)

These analyses not only complement experimental findings but also enhance our understanding by identifying potential binding affinities, binding sites, and conformational changes, thereby validating hypothesized mechanisms of action and guiding the development of more effective therapeutic strategies

Sterile water (without any preservative or acid) is occasionally used in research settings where benzyl alcohol must be excluded from the experimental system

doi: 10.1146/annurev.arplant.53.100301.135154

In addition to its antioxidant properties, glutathione plays a significant role in detoxification by binding to toxins and heavy metals, facilitating their removal from the body

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