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Pharmacol Online 1:385395 Katzenschlager R, Evans A, Manson A, Patsalos PN, Ratnaraj N, Watt H, Timmerman L, Van der Giessen R, Lees AJ (2004) Mucuna pruriens in Parkinsons disease: a double blind clinical and pharmacological study

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It usually occurs due to decreased dopamine production due to dopaminergic neuronal death in the midbrain's substantia nigra, leading to striatal dopamine deficiency, which is responsible for the motor symptoms of PD [2]