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These changes may shift glutamine balance toward increased utilization by immune and intestinal tissues while limiting the capacity of skeletal muscle to replenish circulating pools during periods of metabolic stress (Meynial-Denis, 2016)

Altman MC, Kattan M, OConnor GT, Murphy RC, Whalen E, LeBeau P, et al

In 2019, the US FDA approved the adenosine A2A receptor antagonist istradefylline as an adjunctive treatment to L-DOPA/carbidopa in adult PD patients experiencing OFF episodes or the wearing-off phenomenon

JCI Insight 5 , e133501 (2020)

Biopolymers 91 , 11261134 (2009)

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