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Restriction to English-language publications and the fact that all included studies were conducted in the United States limit the external validity of the results due to lack of ethnic diversity, differences in healthcare systems, and geographic generalisability

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The integration of advanced analytical technologiessuch as capillary electrophoresis-mass spectrometry (CE-MS) and high-resolution MRSis further improving the sensitivity, specificity, and spatial resolution of creatine quantification

Functional analysis demonstrated that miR-491-5p overexpression exerted a tumor suppressor effect by targeting IGF2, and this was also confirmed by the negative correlation between miRNA levels and IGF2 mRNA and protein levels in CRC tissues and cell lines

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[DOI] [PubMed] [Google Scholar] 59.Strinic D., Belosic H.Z., Luetic K., Nedic A., Petrovic I., Sucic M., Zivanovic Posilovic G., Balenovic D., Strbe S., Udovicic M., et al