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3f and Extended Data Fig
But when you have enough glutathione in your body, the antioxidant busts up the free radical partywhich means you can say goodbye to inflammation because those cell-damaging molecules causing it were just kicked out
The host counters these effects through a sophisticated antioxidant defence system, prominently regulated by the nuclear factor erythroid 2 (Nrf2)/antioxidant response element (ARE) signalling pathway 13 , which modulates the expression of antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) 12
[DOI] [PubMed] [Google Scholar] (471).Jarczynska ZD

These results indicate that combined stimulation of the NAc and ALIC is a promising stimulation strategy for DBS treatment of addiction, which is in line with the findings of previous studies [24, 26]
[DOI] [PMC free article] [PubMed] [Google Scholar] 432.Soto I., Howell G.R
