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A plausible explanation could be a reorientation of Lys105 towards GS resulting in a decreased stabilization of the active site thiolate as a leaving group

Therefore, we chose DEHP for further animal experiments, to explore the effects of different doses of DEHP exposure on ovarian function in rats, and to preliminarily explore the possible mechanisms of genes and signal transduction pathways related to ovarian function damage caused by phthalates

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