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Epub 2017 Jun 13

(2021) generated a berberine-loaded phytosome that significantly enhanced insulin sensitivity and lowered total serum testosterone and ovulatory cycles in PCOS models, with better bioavailability than the conventional berberine formulations [193]

Some challenges that need to be tackled are, for example, the search for the molecular mechanisms that balance the consumption of G6P between the PPP and glycolysis, the potential qualitative and quantitative differences in PPP between specific astrocytes and neuronal subtypes across different brain regions, and the involvement of PPP in the etiology and/or progression of neurodegenerative disorders

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[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Wu K.-H., Ho C.-T., Chen Z.-F., Chen L.-C., Whang-Peng J., Lin T.-N., Ho Y.-S