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In the animal Kingdom, S as SO 4 2- and/or S-containing biomolecules are introduced with beverages and food undergoing several metabolic fates, such as, for instance, Met transmethylation and the Cys-producing reactions of transsulfuration [2]

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Notably, some studies have demonstrated that the application of CH223191 in hepatic I/R injury is more effective than DFO in alleviating hepatocyte I/R injury and ferroptosis (21,66,67)

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