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The evidence for an association between gut microbiota and hypertension emanates from studies in murine models showing that rats lacking normal gut flora experience elevated blood pressure [29, 30]

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This suggests that while xanthophylls can inhibit pancreatic lipase in theoretical models, their amphiphilic nature might enhance the formation of emulsions during actual digestion, thereby increasing the breakdown and absorption of fats rather than inhibiting it [34]

Karl M, Rubenstein M, Rudnick C, Brejda J

Early surgical intervention when local recurrence is detected enhances survival, because the dismal outcomes are associated with distant metastasis

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