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This also increases antigen valency which could enhance B cell receptor activation, while the trimeric conformation might also shield non-neutralizing epitopes, such as the membrane-facing side of E1E2 (Fig

10.1016/j.bej.2013.10.005 37 GaoJ.LianZ

A binary solvent comprising of acetonitrile/water 95/5 with 10 mM ammonium acetate as solvent A and acetonitrile/water 50/50 with 10 mM ammonium acetate as solvent B was used for the resolution

The recent discovery of hepcidin has further complicated our understanding of iron metabolism but also established the role of the liver as essential to the maintenance of iron homeostasis.7(See Figure 1)

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