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This activation may result in excessive protein degradation or muscle atrophy, particularly in vulnerable populations such as the elderly or individuals with chronic illnesses [35]

10.1038/sj.onc.1209576 Oncogene 70 XiangN.ZhaoR.SongG.ZhongW

Activity increased approximately ten-fold between 2014 and 2024, underscoring the growing demand for this platform

But is this system truly NADPH-independent

With the changing recommendations for transfusion and treatment regimens for specific patient populations, the relevance of G6PD deficiency in blood donors is increasing, and warrants renewed attention