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Intrinsic factor deficiency, or "congenital pernicious anemia," is a rare autosomal recessive disorder characterized by the lack of gastric intrinsic factor in the presence of normal gastric acid secretion and mucosal cytology (ie, without gastritis) and in the absence of intrinsic factor antibodies found in the acquired form of pernicious anemia

Cons: The necessity of professional administration adds significant cost to the treatment, including fees for healthcare provider time and clinic resources

As previously reported (Section 2.8), following the datasheet recommendations

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(1987) Clinical usefulness of intrathecal injection of methylcobalamin in patients with diabetic neuropathy

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