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To our knowledge, the most studied and understood mitophagy pathway is mediated by PTEN-induced kinase 1 (PINK1) and the E3 ubiquitin ligase Parkin (Narendra et al., 2008

This long-term effect was seen in the phase 2 trial of NRX-101 and the company is attempting to replicate this finding in a larger phase 3 trial

D., Cole, T

Disturbed glutathione antioxidative defense is associated with structural brain changes in neuroleptic-naive first-episode psychosis patients

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The control of myelination during development is regulated by many intrinsic and extrinsic signals both spatially and temporally (reviewed by (Nave & Werner, 2014))