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32 In 2007, Scherz-Shouval et al

FIGURE 1 While many essential steps of the sulfate assimilation and cysteine, methionine and glutathione biosynthesis pathways occur exclusively in plastids, a few enzymes present in the cytosol and mitochondria also come into play, which necessitates a concerted action between enzymes present in different subcellular compartments and intracellular transporters

Cell 102 : 4353 Suzuki Y, Imai Y, Nakayama H, Takahashi K, Takio K and Takahashi R (2001) A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

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Glutathione neutralizes free radicals, preventing cellular damage and inflammation that can lead to these diseases

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