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However, it is not entirely clear whether these (mostly) desirable effects on rapidly proliferating cells are also responsible for causing undesirable effects on non-proliferating sensory neurons, or whether additional pharmacological effects contribute to the development of CIPN

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most metazoans that we assessed encode just one full length CAT sequence, and the evolutionary divergence among them is relatively small compared with the PRX and GPX enzyme families (Table 1 and Fig

This approach can detect changes in the tumors mutational profile over time, allowing for more precise and adaptive treatment strategies that respond to the tumors evolving nature