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The main molecular mechanisms involved in the modulation of eryptosis studied to date, including intracellular calcium levels, ceramide, ROS, NO, changes in cellular energy metabolism, PS externalization, ion channel regulation, Fas-mediated signaling pathways, kinase-associated, and caspases activation, among others represent potential targets for inducing or inhibiting erythrocyte death

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The Mediterranean diet is particularly rich in nutraceuticals which can be used in different fields, such as food, cosmetics, and drugs [86]

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Frye RE, Melnyk S, Fuchs G, et al