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This loop not only stabilizes and amplifies PROX1 expression to cement LEC identity and suppress transdifferentiation towards hematopoietic lineages but also, through regulation of downstream targets like Cx37 (168, 169), orchestrates the alignment of valve endothelial cells, ECM remodeling, and the final morphogenesis of valve leaflets

A casecontrol study involving 41 AD patients and 46 healthy controls showed that hyperhomocysteinemia correlates with cognitive impairment and AD risk due to induction of cortical atrophy and reduced hippocampal activity (Nazef et al

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Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biology
