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J Neurol Neurosurg Psychiatr 1990

1be), which has a high affinity for staining GAGs 21,27

showed that the melanocortin-derived tripeptide KPV produced significant anti-inflammatory effects in DSS colitis and CD45RBhi transfer colitis models two of the most commonly used and accepted IBD research paradigms.1 Critically, the anti-inflammatory effect persisted even in animals with a nonfunctional MC1R receptor, confirming that KPV's action does not depend on melanocortin signaling

Patients know exactly what to do on day 1 and exactly what we are checking at day 90

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Pfeufer, E