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Simultaneously, low levels of p53 downregulate peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1), mitochondrial transcription factor A, and p53-induced ribonucleotide reductase M2B subunit to impair mitochondrial function [101]

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-glutamyl transferase activity and inhibition Degradation of GSH conjugates depends on the activity of -GT activity, an enzyme that is highly abundant in all tissues, especially liver, and that converts IGSH rapidly to ICGS

The liver produces most of the GGT in the blood [1, 2, 3]

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