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DOI: 10.1016/j.ceb.2014.11.002 Morinaga, H., Mayoral, R., Heinrichsdorff, J., Osborn, O., Franck, N., Hah, N., Walenta, E., Bandyopadhyay, G., Pessentheiner, A.R., Chi, T.J., Chung, H., Bogner-Strauss, J.G., Evans, R.M., Olefsky, J.M., Oh, D.Y

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Research has recognized ferroptosis as a possible pathogenic mechanism associated with lumbar disc herniation, although detailed mechanistic investigations remain scarce

Since these conditions stem from a sustained imbalance between energy intake and expenditure, the primary approach to treatment emphasizes lifestyle changes specifically, reducing calorie consumption and increasing physical activity to promote a negative energy balance (Gomez-Zorita et al

In rodents, the PPP is the primary mechanism of glucose metabolism in oligodendrocytes of the thalamus with low ATP/adenosine diphosphate (ADP) ratios, while glycolysis is the primary mechanism in the cortex and hippocampus with high ATP/ADP ratios (Kleinridders et al

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