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Glutamine plays a crucial role in the glutaminolysis pathway, where it is converted into glutamate and -ketoglutarate, intermediates in the tricarboxylic acid (TCA) cycle [48]

10.1016/j.jgr.2020.02.004 66 RenJ

Many factors can deplete the amount of glutathione in your body, including pollution, stress, infections, poor sleep, a diet low in plant foods, and even simply becoming older, as youll make less of this valuable antioxidant as you age

Overexpression of GPX4 protects mouse cardiomyocytes during IR, whereas GPX4 deficiency exacerbates damage (89)

Our in vitro experiments on human primary monocytes show that the glutathione metabolism is involved in the regulation of the acute response to BDG at the transcriptomic and molecular levels, yet further studies are required to evaluate the functional impact of this phenomenon in vivo

The present study delved into the molecular mechanisms underlying OSA, emphasizing the role of A2AR in modulating these processes