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Sudden changes in diet can lead to occasional discomfort, so slowly incorporating new foods allows your dog's digestive system to adjust and supports normal GI health and function

Gastroenterology 145 , 312319 (2013)

Vaughan M, Berger JE, Steinberg D

(The term P450 refers to the 450-nm absorption peak characteristic of these heme proteins when they bind carbon monoxide.) The net result of a cytochrome P450-dependent oxidation reaction is: The reaction proceeds when the drug binds to the oxidized (Fe 3+ ) cytochrome P450 to form a complex, which is then reduced in two sequential oxidation/reduction steps as outlined in Figure 4-2A

Contamination introduction Failing to clean vial stoppers before needle insertion transfers bacteria into the solution