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Consistent with our study, Deepashree et al., (2019) [138] observed an age-related decline in antioxidant defenses following ethanol-induced oxidative stress on Drosophila and Guevara et al., (2011) [139] detected a significant age-related reduction in antioxidant enzyme activities, including SOD and catalase, in rat brains

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Clone with a Q45R substitution showed the best activity and was named G2 (Supplementary Fig

Since the early 2000s, the discovery of multiple regulated cell death programmes has intensified interest in targeting these maladaptive traits that cancer cells employ to resist cellular demise