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Given the high consumption of free glutamine by intestinal cells, glutamine dipeptides have been studied as an alternative for transposing the intestinal barrier and increasing the bioavailability of this amino acid to cells of the immune system

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3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

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Studies have shown that a three-month course of intravenous methylprednisolone pulse therapy significantly reduces seizure frequency, improves VSMS, and improves electroencephalographic parameters, with no serious adverse effects reported

Malfunction of astrocyte-mediated GABAergic regulation is supported by findings in GABRB2 -knockout mice, which exhibit astrocytic atrophy, degeneration of parvalbumin-expressing cortical interneurons, neuroinflammation and oxidative stress, aligning with key pathological features of schizophrenia 302