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The development of clinically useful AQP4 inhibitors has proved difficult for several reasons 570

doi: 10.1016/s0891-5849(98)00041-0

"Superoxide Ion: Generation and Chemical Implications"

Sweet MG, Schmidt-Dalton TA, Weiss PM, Madsen KP

The co-suppression of glutamine and one-carbon metabolism has been demonstrated to enhance the anticancer effect of drugs utilized in patients diagnosed with undifferentiated thyroid cancer (ATC), while concurrently mitigating the development of drug resistance to a certain extent
