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In the cytosol, glutamic-oxaloacetic transaminase 1 (GOT1) catalyzes the conversion of aspartate and -KG into oxaloacetate and glutamate

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Regulation of lifespan by neural excitation and REST

IL-27 suppresses the transcription of HIV-1 and preferentially inhibits HIV-1 replication in macrophages compared with CD4 + T cells and activates multiple IFN-inducible genes (ISG) in macrophages like IFN-, suggesting that IL-27 inhibits HIV-1 replication in macrophages via a mechanism similar to that of IFN- [138140]