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Regarding treatment, treatment of chronic HCV infection with peginterferon + ribavirin showed variable efficacy depending on the genotype with sustained virological response (SVR) rates of 4258% 21,22,23 , 80%, 66% 24 or 6369% 25 for GT1, GT2, GT3 or GT4, respectively

TMAO in cardiomyocytes triggers TGF1/Smad3/p65 NFB signaling pathways and lowers energy metabolism and mitochondrial function by disrupting pyruvate and fatty oxidation, as well as the TCA cycle

Increasing muscle carnitine content alters muscle fuel metabolism and improves exercise performance in humans

The fact that the non-MS group was not composed of healthy controls may be considered a limitation of our study

Effects of L-carnitine on the pyruvate dehydrogenase complex and carnitine palmitoyl transferase activities in muscle of endurance athletes

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