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Our group has previously discussed the role of the gut microbiota in mediating obesity-induced inflammation and its systemic complications, but whether this involves oxidative stress or is linked to uterine fibroid development remains to be investigated [39]

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Additionally, MSI-H tumors are strongly associated with the loss of MLH1 protein expression in sporadic tumors, whereas familial tumors often exhibit a loss of both MLH1 and MSH2 protein expression ( PTEN ), further enhance the risk of developing EC

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