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Inhibition or siRNA-mediated knockdown of HSL reduced efferocytosis and downregulated the expression of M2 markers, including CD206, CD163, CD200R1, and Annexin A1, while promoting a pro-inflammatory state
Hill G, Millar W, Connelly J
Combining it with B12 might enhance these effects
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Boosting HSL activity could help improve efferocytosis and promote inflammation resolution, offering a potential therapeutic angle
