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By stimulating the white-to-brown conversion hormonally, we observed that a rapid drop of GSH concentration and decreased GSH/GSSG ratio accompany the up-regulation of brown-related genes and that such an event is significantly blunted by supplementing adipocytes with GSH ester

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In this study 0 was defined as no changes

The GO database was used to annotate the functions of all differentially expressed proteins

A computational study also supports that the compounds having more electron donating potentials are better inhibitors of hydroperoxides that suggest many of the antioxidant agents [6267]

Lastly, NBDHEX is not a substrate for the P-glycoprotein export pump but promotes cysteine-dependent apoptosis in cells overexpressing P-gp and may be used to treat P-gp-positive tumors [165]