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This interpretation is further supported by our finding of higher 3-hydroxybutyric acid levels in the hyperthyroid group, consistent with ketone overproduction when acetyl-CoA generation surpasses tricarboxylic acid cycle capacity

A.CantaA.ChiorazziA

J Endocr Soc

Various factors, such as skin aging, inflammation, sunlight exposure, wound healing, and fibrosis, can promote ECM remodeling, potentially resulting in aberrant ECM modifications (Pfisterer et al, 2021), which may modify the presentation of ECM ligands and alter substrate stiffness

ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production

Brown AC, Macrae HS, Turner NS