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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

FIGURE 7 4 Discussion Inflammatory lung injury is a hallmark pathological feature of pneumonia caused by diverse infectious and non-infectious stimuli, including bacterial endotoxins, allergens, and environmental irritants ( In this study, we utilized targeted metabolomic profiling to investigate common metabolic alterations in two mechanistically distinct murine models of lung injuryLPS- and papain-induced inflammation
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