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Reduced glutathione or GSH serves as the cornerstone for maintaining: Cellular redox homeostasis [1] Neutralizing free radicals [1] Heavy-metal detoxification [1] Regulate pigmentation pathways [1] The Bioavailability Paradox Despite its unmatched therapeutic potential, standard oral glutathione suffers from significant biological limitations

Fecal microbiota transplantation and antibiotic treatment attenuate naloxone-precipitated opioid withdrawal in morphine-dependent mice

Orange: Doohan and colleagues

Neurochem Res 44(10):22732279

Unlike many other antioxidants, Glutathione is not obtained primarily from the diet but is synthesised within the body using three amino acids: cysteine, glycine, and glutamic acid