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There are several processes that contribute to mitochondrial quality control, including UPR mt , mitophagy, mitochondrial membrane dynamics, and mitochondrial biogenesis 13,89

Normalization of the rate of fatty acid oxidation in skeletal muscle and normalization of hyperinsulinemia, hyperglycemia, and significant improvement in hepatic insulin sensitivity was observed in the double-transgenic MKR/CD36 mice (115)

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