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Although cyanocobalamin is more readily absorbed, much of it is excreted through the urine before it can reach the cells Cyanocobalamin vs Hydroxocobalamin In comparison to hydroxocobalamin, cyanocobalamin has a significantly worse absorption rate and storability, which is why today mostly hydroxocobalamin is used in B12 injections

However, clinical trials in humans have demonstrated mixed results

Other recognized medical uses of B12 injections include: Megaloblastic anemia

People with a known allergy to cobalamin or cobalt should avoid them, and those with Leber's hereditary optic neuropathy should not receive B12

This is thought to be true because of vitamin Bs positive effects on your metabolism

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