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J., Chang, S

[26] In severe anemia, there may be signs of a hyperdynamic circulation: tachycardia (a fast heart rate), bounding pulse, flow murmurs, and cardiac ventricular hypertrophy (enlargement)

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de Rooij DJ Hla-Dr Antigens and Proteinuria Induced by Aurothioglucose and D-Penicillamine in Patients with Rheumatoid Arthritis

For some parameters (e.g., proteinuria involving proteins of low relative molecular mass) minor dysfunctions at the tubular level will result in deviations of several orders of magnitude from reference values, whereas the same relative change in other parameters (e.g., brush-border antigens, enzyme activities) may indicate severe tubular injury