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While Nrf2 is experimentally proven to have a protective role in numerous airway diseases [336], the signalling pathway in collaboration or contradiction with NF-B is still not clear

608 By combining these agents, Trikafta addresses both the folding defect and the gating dysfunction of CFTR, leading to markedly enhanced lung function, reduced pulmonary exacerbations, and improved quality of life in patients with at least one F508del mutation, accounting for the majority of CF cases

To estimate initial velocities of unwinding, readings obtained after ATP injection were fit to a first-order rate equation

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Conflict of interest The University of Oxford holds a patent for use of MuSK for antibody assays, licensed to Athena Diagnostics

doi: 10.1155/2023/1387665