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REFERENCES Kim YS, Leventhal BL, Koh YJ, Fombonne E, Laska E, Lim EC, et al

Since the discovery of the first xCT inhibitor erastin [80], derivatives like imidazole ketone erastin (IKE) was developed to improve solubility meanwhile introducing lysine-reactive ketone as a covalent warhead, thereby achieving nanomolar IC 50 [81,82]

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