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Dopamine in the human body can readily undergo oxidation to form intermediates, including quinones and indoles that could self-assemble into polydopamine nanoparticles, giving photothermal conversion capabilities to the nanocomposite

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In this process, syntaxin-17 is recruited to Parkin-dependent mitochondria-derived vesicles (MDVs) and subsequently forms a soluble NSF attachment protein receptor (SNARE) complex with SNAP29 and VAMP7 to facilitate the late endosomes/lysosomes fusion [161, 162]