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Description
(Nature Communications) demonstrated that selective NNMT inhibition in diet-induced obese mice produced significant reductions in fat mass and improvements in insulin sensitivity without caloric restriction
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[PubMed | ClinicalTrials.gov | DOI] Garvey WT, Batterham RL, Bhatt DL, et al
The compound belongs to a class known as NNMT inhibitors
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GLP-1 Agonists (Semaglutide, Tirzepatide) GLP-1 receptor agonists like semaglutide and tirzepatide produce fat loss primarily through appetite suppression and reduced caloric intake rather than direct fat cell targeting
