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BMC Gastroenterol 12(1):18 Zhang DK, He FQ, Li TK, Pang XH, Cui DJ, Xie Q, Huang XL, Gan HT (2010) Glial-derived neurotrophic factor regulates intestinal epithelial barrier function and inflammation and is therapeutic for murine colitis

However, because the continuous oxidation of lactate rapidly reduces newly salvaged NAD, this compensatory upregulation fails to rescue glycolytic flux

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[DOI] [PMC free article] [PubMed] [Google Scholar] Jungbluth M, Mosch HU, Taxis C

So they found that by studying real patients, using the FDA-approved tests, they miss a little bit over half