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Preliminary findings suggest that test subjects in one of the Fragment 176-191 groups may have experienced a notable reduction in fat tissue mass, with an average weight loss of approximately 5.7 pounds

[PMC free article] [PubMed] [Google Scholar] 28.Gerdts J, et al

In severe cases, patients may develop visual disturbances due to optic neuropathy

Thus, by nature of its different affinity for the reduced folate carrier compared with folate receptors, the binding and transport of UMFA may selectively affect those tissues with exposed folate receptors that facilitate cellular entry and possibly signaling