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Description
Experimental injury, a surgical incision in the plantar aspect of the rat hind paw, leads to a remarkable reduction in paw withdrawal threshold to mechanical stimuli for several days, representing mechanical hyperalgesia [10]

Other processes involving folate coenzymes include generation and use of formate and methylation of transfer RNA

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These results suggest that mitochondrial dysfunction may become an essential cause of HD pathology

This view is consistent with results from nutritional studies involving multiple fish species
