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Both approaches have their place, but chronic conditions often respond better to the gradual approach

Interestingly, while mitochondrial transplantation led to sustained increases in ATP production and OCR in P301L SH-SY5Y cells, the MMP returned to its baseline level after 48 h

A sequence alignment of the deduced mature peptides is shown in Figure 4

ACS Chemical Biology , 11 ( 10 ), 26932705

OS plays a primary role in the pathogenesis of DM (125, 126) as manifested through many enzymatic, non-enzymatic, and mitochondrial mechanisms (127)

By acting as a competitive inhibitor of CD44hyaluronic acid interactions, m11 is expected to interfere with CD44-mediated functions