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Translating Rational Combinations Targeting RAS into the Clinic

HHcy is also frequently reported in patients with metabolic disorders, including T2D [5] and overweight/obesity [4,26], suggesting that dysregulation of the transsulfuration pathway may play a role in the onset, progression and/or complications not only of CV diseases but, more broadly, of cardiometabolic disorders [5]

However, reviews providing a practical treatment pathway for the management of melasma are limited

[PMC free article] [PubMed] [Google Scholar] 42.Averill-Bates D.A

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