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Later analytical work characterized the in vitro metabolism of AOD-9604 how the peptide is broken down and what metabolites appear primarily in the service of anti-doping detection methods rather than efficacy

Increases SIRT-1 activity as a result of enhanced NAD+ salvage, leading to beneficial epigenetic and metabolic reprogramming, including increased oxidative phosphorylation (OXPHOS) and muscle stem cell activation 1-3

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[8] Stress and exercise: Intense training, chronic stress, and certain health conditions all increase your bodys NAD+ demand, raising the effective dose you need to see results