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Glutathione synthetase deficiency is the most frequently recognized disorder and, in its severe form, it is associated with hemolytic anemia, metabolic acidosis, 5-oxoprolinuria, central nervous system (CNS) damage and recurrent bacterial infections

Journal of Clinical Investigation 123(3):966-972

The protective effect of neutralizing antibodies in SARS-CoV-2 infected individuals is not yet well defined

This Review highlights the central role of astrocytes in brain lipid homeostasis and reviews evidence for astrocytic lipid dysregulation in various neurodegenerative diseases, including Alzheimer disease, Parkinson disease, amyotrophic lateral sclerosis, frontotemporal dementia and Huntington disease

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Supplementing with oral glutathione under conditions in which intracellular glutathione status is compromised can restore tissue glutathione and promote ROS metabolism, thereby mitigating tissue atrophy, according to a 2017 study published in the World Journal of Gastroenterology